Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_truncNotch.phenotype_absentNotch_versus_truncNotch.cls #truncNotch_versus_absentNotch |
| Phenotype | phenotype_absentNotch_versus_truncNotch.cls#truncNotch_versus_absentNotch |
| Upregulated in class | absentNotch |
| GeneSet | NCI_HEDGEHOG SIGNALING EVENTS MEDIATED BY GLI PROTEINS |
| Enrichment Score (ES) | -0.73256934 |
| Normalized Enrichment Score (NES) | -1.5930712 |
| Nominal p-value | 0.004201681 |
| FDR q-value | 0.33055422 |
| FWER p-Value | 0.735 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ARRB2 | 2060441 | 803 | 0.543 | -0.0033 | No | ||
| 2 | SUFU | 6650181 | 1169 | 0.409 | 0.0072 | No | ||
| 3 | PRKACA | 2640731 4050048 | 1442 | 0.342 | 0.0177 | No | ||
| 4 | SIN3B | 6650253 | 2753 | 0.139 | -0.0426 | No | ||
| 5 | CSNK1D | 4280280 4480167 6450600 | 2795 | 0.134 | -0.0349 | No | ||
| 6 | RBBP4 | 6650528 | 3014 | 0.113 | -0.0383 | No | ||
| 7 | SMO | 5340538 6350132 | 3483 | 0.079 | -0.0577 | No | ||
| 8 | CSNK1G1 | 840082 1230575 3940647 | 3660 | 0.069 | -0.0621 | No | ||
| 9 | GNAZ | 6130296 | 4438 | 0.044 | -0.1007 | No | ||
| 10 | PTCH1 | 430278 | 4914 | 0.034 | -0.1238 | No | ||
| 11 | GLI3 | 5690148 | 5064 | 0.031 | -0.1296 | No | ||
| 12 | GLI2 | 3060632 | 6229 | 0.017 | -0.1910 | No | ||
| 13 | MTSS1 | 780435 2370114 | 9421 | 0.003 | -0.3626 | No | ||
| 14 | FBXW11 | 6450632 | 9783 | 0.002 | -0.3818 | No | ||
| 15 | GNAI3 | 4670739 | 9818 | 0.002 | -0.3835 | No | ||
| 16 | XPO1 | 540707 | 11119 | -0.001 | -0.4534 | No | ||
| 17 | AKT1 | 5290746 | 11232 | -0.001 | -0.4593 | No | ||
| 18 | GLI1 | 4560176 | 11448 | -0.002 | -0.4708 | No | ||
| 19 | GNAI1 | 4560390 | 13372 | -0.010 | -0.5736 | No | ||
| 20 | SHH | 5570400 | 13531 | -0.011 | -0.5813 | No | ||
| 21 | SAP18 | 3610092 | 13801 | -0.014 | -0.5948 | No | ||
| 22 | FOXA2 | 540338 5860441 | 14017 | -0.016 | -0.6052 | No | ||
| 23 | CSNK1A1 | 2340427 | 14088 | -0.017 | -0.6077 | No | ||
| 24 | RAB23 | 2970075 | 14193 | -0.019 | -0.6119 | No | ||
| 25 | GNAO1 | 2510292 6590487 | 14218 | -0.019 | -0.6117 | No | ||
| 26 | MAP2K1 | 840739 | 15876 | -0.103 | -0.6934 | No | ||
| 27 | GNG2 | 2230390 | 16167 | -0.135 | -0.6991 | No | ||
| 28 | CSNK1G3 | 110450 | 16790 | -0.251 | -0.7141 | Yes | ||
| 29 | RBBP7 | 430113 450450 2370309 | 17096 | -0.331 | -0.7061 | Yes | ||
| 30 | IFT172 | 3800372 7100400 | 17142 | -0.342 | -0.6834 | Yes | ||
| 31 | KIF3A | 5050348 6650079 | 17303 | -0.385 | -0.6637 | Yes | ||
| 32 | GNB1 | 2120397 | 17307 | -0.386 | -0.6355 | Yes | ||
| 33 | HDAC1 | 2850670 | 17368 | -0.409 | -0.6086 | Yes | ||
| 34 | GSK3B | 5360348 | 17444 | -0.435 | -0.5807 | Yes | ||
| 35 | PRKCD | 770592 | 17479 | -0.447 | -0.5496 | Yes | ||
| 36 | CSNK1E | 2850347 5050093 6110301 | 17665 | -0.518 | -0.5214 | Yes | ||
| 37 | LGALS3 | 2120239 | 17696 | -0.538 | -0.4835 | Yes | ||
| 38 | CREBBP | 5690035 7040050 | 17707 | -0.541 | -0.4442 | Yes | ||
| 39 | SIN3A | 2190121 | 18047 | -0.708 | -0.4104 | Yes | ||
| 40 | CSNK1G2 | 3060095 4730037 | 18124 | -0.763 | -0.3583 | Yes | ||
| 41 | PIAS1 | 5340301 | 18308 | -0.946 | -0.2985 | Yes | ||
| 42 | SPOP | 450035 | 18384 | -1.060 | -0.2245 | Yes | ||
| 43 | HDAC2 | 4050433 | 18463 | -1.273 | -0.1351 | Yes | ||
| 44 | SAP30 | 5080735 | 18567 | -1.947 | 0.0026 | Yes |
